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- In addition, this patient additionally had polycythemia, likely secondary to high-dose testosterone.
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- Patients also could also be taking concomitant stimulants, corresponding to ephedra, which can confound knowledge and the potential for opposed events.
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Discover why industry-leading corporations across the globe love our data. IPinfo’s accurate insights fuel use circumstances from cybersecurity, information enrichment, web personalization, and far more. Effects of testosterone on coronary vasomotor regulation in males with coronary heart disease. Manifestation of extreme coronary coronary heart disease after anabolic drug abuse. Relationship between endogenous sex hormone levels, lipoproteins and coronary atherosclerosis in males present process coronary angiography. Basaria S, Dobs AS. Risks versus advantages of testosterone remedy in aged males.
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In addition, the information out there in the literature does not account for the steroid type or dose, as neither may be identified. Patients also may be taking concomitant stimulants, such as ephedra, which can confound information and the potential for opposed occasions. It is likely that the frequency of cardiac events is underreported in the medical literature. Supraphysiologic doses of anabolic-androgenic steroids , which embrace more than 30 natural and artificial derivatives of testosterone, might cause a wide spectrum of medical sequalae.
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We report a case of an acute ST-segment elevation myocardial infarction in a patient with traditional cardiac danger components utilizing supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this affected person additionally had polycythemia, probably secondary to high-dose testosterone. The affected person underwent successful percutaneous intervention of the best coronary artery. Physicians and patients should concentrate on the scientific penalties of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996). Moreover, a component of endothelial dysfunction has been proposed, which can contribute to irregular vessel reactivity.
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